Fat Supplementation of Human Milk with MCT Oil for Promoting Weight Gain in Preterm Infants

Background: The addition of medium chain triglycerides is preferable as they are more easily digested and quickly absorb in bloodstream than long fat provide ready supply energy by increasing fatty acid bioavailability. Modular products like micro lipids medium-chain triglyceride (MCT) oils now focused a supplementation. rate weight gain with MCT not well known, there very less research done Pakistan. Objective: To determine the effect oil supplemented human milk compared un fed to preterm infants on promoting gain. Study Design: Randomized controlled trial Setting: This study was conducted Department Neonatology, Children Hospital, PIMS, Islamabad, Pakistan from 20th August 2022 February 2023. Methodology: after approval institutional ethical committee. A total 160 fulfilling inclusion criteria enrolled informed consent parents. patients were receiving enteral feeding within neonatology department hospital included randomly assigned Group NF (receiving 20 ml without oil), F 20ml 1 fat). Primary outcomes including growth term at measured 1st ,5th 10th day intake admission. Secondary outcome intolerance, diarrhoea, sepsis necrotising enterocolitis. All data collected form questionnaire. statistical analysis using SPSS version 20. Results: One sixty low birth analyzed this study. divided into two groups: NF, demographic details. first day, fifth tenth noted that frequency improved taking supplementation or We found gradually their weights NF. On 75% reaches between1400-1490 gm (p<0.001). average daily (g/kg). 12.2 A, 13.6 group B calculated first. shifted 14.9 then it further increased 15.6 C, 15.8 D. Practical Implication: humans significant source energy. In an underdeveloped State short resources, can be useful substitute for due its high content. Few studies have been area thus far. Previous had number participants produced contradictory findings. Therefore, carried out compare efficacy them supplement. Conclusion: Our shows those added breast milk. provides regarding selection use over non-supplemented reduces morbidity mortality insufficiency nutrients. Keyword: Fat supplementation, oil, milk, infants, rate.